HEY DACS85 I've done the drive twice and it really matters when you leave. If you go on "the 5" and you get to the Los Angeles area anywhere between 4-6 pm you're going to add two hours to your trip.
Menik, how long did it take us?
I feel like it took about 7 hours from SF area to LA area and then about 1.5 hours to get into Indio Area.
You can avoid the two added hours in LA by going 5->138->15. It takes a bit longer than 5 does when it's empty, because the speed limit is slower and there's a chance you'll get stuck behind something *really* *slow*, but it beats the stress of LA traffic, and it's kinda a pretty view.