If Foo Fighters get an album out before May of next year I feel they're a sure bet, unfortunately.
I'm also thinking Mumford & Sons will take the Phoenix/Black Keys/Kings of Leon/Muse/Killers slot of hot new blockbuster band. And I can't stand them.

I'm crossing my fingers for some variation of Beck/Outkast/Daft Punk/Nine Inch Nails but that would be way too 90's I suppose. They're gonna have to slip some bullshit like Mumford in there to bring in the KROQ crowd.